Building Resilience in Uncertainty (How to Support Your Brain)

Feb 18, 2026 | Leadership, Stress

The Grey Areas

When I first became a lawyer, I thought the law would mostly involve black-and-white thinking. Clear rules and case law. Predictable outcomes. Right and wrong answers.

But I quickly learned the law – like life – is full of grey areas. I struggled with trying to predict outcomes for my clients, and the uncertainty was stressful.

Right now, many professionals are swimming in uncertainty. Will AI transform or eliminate parts of your role? How will economic shifts affect your organization’s funding? What will political changes mean for your work? Which skills will matter in five years?

Uncertainty, Stress and Your Brain

Our brains are prediction machines. They’re constantly processing information, scanning for patterns, and forecasting what’s coming next. This prediction system helped our ancestors survive by anticipating threats and opportunities.

So when the future becomes unpredictable, the brain senses a threat.

Even a small amount of uncertainty can activate your amygdala, triggering the fight-flight-freeze response. And the less information you have for the brain to predict, and the greater your stress response.

A remarkable study from 2016 looked at the stress of participants as they played a computer game where they occasionally received small electric shocks. The study found that when participants were uncertain about when shocks would come, they were more stressed than when they knew they would be shocked.

Essentially, the stress of the pain was less than the stress of the uncertainty!

Given all of today’s uncertainty, what should you do?

The Two Paths Through Uncertainty

The least helpful thing you can do is deny or suppress the problem. That won’t relieve your stress; instead, it will mount and show up in other ways—sudden anger, anxiety, burnout, or poor decisions.

Stress is a signal to the brain to DO something, to act. But that “something” isn’t always a physical action. It might be a choice.

Choice 1: Choose to Act

When you’re drowning in uncertainty, fear, or anxiety, you’re stuck in the threat-focused parts of your brain. The antidote, according to neuroscience, is to activate the parts that thrive on structure, focus, analysis, and problem-solving.

Feeding these systems through purposeful action calms the stress of uncertainty and rewards you with dopamine.

Ask yourself: Can I influence this outcome? Is there action I can take that might actually matter?

If the answer is yes, then it’s time to act.

Practical strategies for the “Act” path:

  1. Create structure and plans. Your brain craves predictability. Build it where you can. Develop if-then scenarios for different outcomes. Create a schedule that gives your days shape and rhythm. Having structure doesn’t mean rigidity—it means having a framework that frees up mental energy for what matters.
  2. Do your research. Gather information. Ask questions. Learn about the AI tools changing your field. Understand the economic landscape. Talk to people who’ve navigated similar transitions. All of this problem-solving is hard work for your brain, but if you can get closer to knowing an outcome, you can take wise action.
  3. Build relevant skills. If you’re worried about staying relevant in your field, invest in skills that AI can’t replicate: judgment, relationship-building, creative problem-solving, strategic thinking. Take a course. Find a mentor. Experiment with new approaches.
  4. Stay active. Exercise isn’t just good for your body; it’s essential for managing uncertainty. Physical activity reduces stress hormones like cortisol and adrenaline while stimulating endorphins that boost your mood. Movement literally helps your nervous system process and regulate stress.
  5. Connect with others. Our nervous systems are wired for connection, and social connection supports both mental and physical health. Reach out to colleagues navigating similar challenges. Join a professional community. Share what you’re learning. Sometimes action means asking for support.

Remember that problem-solving is taxing on the brain, so start with small steps, take breaks and build momentum with time. And when your brain knows you’re getting closer to clarity, you’ll be rewarded with a dopamine hit that will help you stay the course.

Choice 2: Choose to Let Go

But what if you’ve done all you can do? What if you truly cannot see a path to clarity or possibility?

Ask yourself: What is within my control?

If the answer is truly nothing – other than your mindset, which you can always control – then no amount of worry or stress will help resolve the situation. In this case, the best action may be to decide to let it go.

Practical strategies for the “Let Go” path:

  1. Pause and name what you’re feeling. Slow down. Get curious about what’s actually happening in your body and mind. Just naming your feelings (e.g., “I’m feeling anxious” or “I’m feeling frustrated”) can deactivate your amygdala and reduce the threat response. Don’t judge the feelings. Simply observe them.
  2. Practice letting your nervous system calm. Yoga, meditation, and breathing exercises stimulate your parasympathetic nervous system for the calming “rest and digest” response. Even 10 minutes can make a difference. Try a simple breathing practice: breathe in for four counts, hold for four, out for six. The longer exhale signals safety to your nervous system.
  3. Spend time in nature. Research shows that being in nature lowers stress hormones after just 20 minutes. Take a walk. Sit outside. Let your nervous system register that in this moment, right now, you’re safe.
  4. Find meaning and moments of aliveness. Do activities that create feelings of connection, gratitude, joy, or purpose. These positive emotions help counteract the effects of stress on your body and brain.
  5. Allow for ambiguity. Here’s something counterintuitive: being in limbo, though uncomfortable, isn’t necessarily bad. When you stop trying to predict and solve, the brain can opens to new ideas and new connections. And here, AI cannot replace us, because only the human mind can produce such insights. In this way, uncertainty can be a rich, creative space full of possibilities and new directions.

The Wisdom to Know the Difference

The most resilient professionals don’t eliminate uncertainty. They learn to navigate it skillfully.

They develop the wisdom to know when to act and when to let go; when to push harder and when to surrender; when to plan and when to trust.

This discernment is itself a skill you can develop.

Start by pausing when you feel that familiar stress of uncertainty. Ask: Can I influence this? Is there action I can take that might matter? If yes, make a plan and act. If no, acknowledge what’s beyond your control and practice letting go.

Your brain will thank you. And you’ll find that you can not only survive uncertainty, but you can grow through it.

Over to You

What uncertainties are you or your organization facing right now? Have you identified whether the path forward is to act or to let go? I’d love to hear how you’re navigating these uncertain times.

I’ll leave you with one of my favorite quotes from Dr. Viktor Frankl: “Everything can be taken from a man but one thing: the last of the human freedoms—to choose one’s attitude in any given set of circumstances, to choose one’s own way.”

If you, your organization or team is looking to build resilience skills for uncertain times, let’s connect.

Photo by Jakub Kriz on Unsplash

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Jen Riggs Blog

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Jennifer is the creator of Pathways to Change, a framework for mindful leadership development that integrates coaching, neuroscience, mindfulness and mind-body principles.

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